Preheat your oven to 350°F (175°C).
In a medium bowl, combine the ground beef, bread crumbs, hamburger seasoning, garlic powder, salt, and pepper.
Shape the mixture into 16 small balls. Place them on a baking sheet and press down just a bit to flatten.
Pop them in the oven for 10 minutes until cooked through.
Take them out and add a quarter slice of cheddar, a piece of lettuce, a pickle, and half a cherry tomato on top of each.
Stick a toothpick through each bite for easy snacking and serve them up!